Infertility effects 15% of couples worldwide. Male factors contribute to 50% of these cases. Our research program is working to understand the genetic and molecular underpinnings of Non-obstructive Azoospermia (NOA), where a severe defect in spermatogenesis is present. Using single cell sequencing techniques, state-of-the-art computational approaches, and 3-D bioprinting, we are working to develop a regenerative medicine platform to treat men with severe infertility. We are also working to develop technology for optimizing sperm selection in assisted reproductive technologies. Our research is highly collaborative with complimentary field such as molecular biology, genetics, biomedical engineering, computer science, and mechanical engineering.